e-CAB 8 de setembre. Noves entrades

Noves Noticies i links del The National Prescribing Centre's Current Awareness Bulletin (eCAB) contains links to the latest health news, including clinical news, health and social care guidance, publications and policy.

National Prescribing Centre (NPC): http://www.npc.co.uk

· Dispensing with Repeats: A practical guide to repeat dispensing (2nd edition, 2008; 32-page pdf)

http://www.npci.org.uk/medicines_management/patients/repeatdisp/resources/dwr_for_web.pdf

NPCi Blog http://www.npci.org.uk/blog/
· MeReC Rapid Review: Cholesterol measurements in the first few years of statin treatment may mislead (updated) http://www.npci.org.uk/blog/?p=185

BBC Health News: http://news.bbc.co.uk/1/hi/health/default.stm
· Weekly diabetes jab hopes raised http://news.bbc.co.uk/1/hi/health/7603676.stm

BMJ: http://bmj.com/
· News: People in deprived areas of England are less likely to survive cancer http://www.bmj.com/cgi/content/full/337/sep08_1/a1598?q=rss_home

· Clinical review: Management of sickle cell disease http://www.bmj.com/cgi/content/full/337/sep08_1/a1397?q=rss_home
InfoPOEMs: http://www.essentialevidenceplus.com/

· Sildenafil may improve antidepressant-induced sexual dysfunction in women http://www.essentialevidenceplus.com/infopoems/dailyInfoPOEM.cfm?view=122735

National electronic Library for Medicines (NeLM): http://www.nelm.nhs.uk

· RCT: Effect of the frequency of self-monitoring blood glucose in patients with type 2 diabetes treated with oral antidiabetics http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/RCT-Effect-of-the-frequency-of-self-monitoring-blood-glucose-in-patients-with-type-2-diabetes-treated-with-oral-antidiabetics/
·

DH issues draft document for comment: pandemic influenza - surge capacity and prioritisation in health services http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/DH-issues-draft-document-for-comment-pandemic-influenza---surge-capacity-and-prioritisation-in-health-services/
·

Payment by Results for kidney dialysis project group: interim report, June 2008 http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Payment-by-Results-for-kidney-dialysis-project-group-interim-report-June-2008/

· Editorial: identifying safety signals in clinical trials around the link between ezetimibe and cancer http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Editorial-identifying-safety-signals-in-clinical-trials-around-the-link-between-ezetimibe-and-cancer/

· Anticonvulsants and possible suicidality – communicating risks when there’s not much data http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Anticonvulsants-and-possible-suicidality--communicating-risks-when-theres-not-much-data/

· King's Fund: Widespread variations remain in local NHS spending http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Kings-Fund-Widespread-variations-remain-in-local-NHS-spending/

· ‘Behind the Headlines’ assessment of reports on new research finding no link between MMR vaccination and autism http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Behind-the-Headlines-assessment-of-reports-on-new-research-finding-no-link-between-MMR-vaccination-and-autism-/

· US-based economic evaluation of sunitinib maleate for the first-line treatment of metastatic renal cell carcinoma http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/US-based-economic-evaluation-of-sunitinib-maleate-for-the-first-line-treatment-of-metastatic-renal-cell-carcinoma/

· Anatomy of a “seeding trial” – a clinical trial as drug marketing http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Anatomy-of-a-seeding-trial--a-clinical-trial-as-drug-marketing/

· Horizon scanning: exenatide once-weekly non-inferior to twice daily in type 2 diabetes? http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Horizon-scanning-exenatide-once-weekly-non-inferior-to-twice-daily-in-type-2-diabetes-/

· Systematic review: studies reporting positive and statistically significant outcomes more likely to be published? http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Systematic-review-studies-reporting-positive-and-statistically-significant-outcomes-more-likely-to-be-published--/

· Horizon scanning: experimental osteoporosis drug lasofoxifene (Fablyn®) linked to higher number of deaths versus placebo http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---September/08/Horizon-scanning-experimental-osteoporosis-drug-lasofoxifene-Fablyn-linked-to-higher-number-of-deaths-versus-placebo/

· Acceleration and augmentation of antidepressants with lithium for depressive disorders: two meta-analyses of randomized, placebo-controlled trials http://www.nelm.nhs.uk/en/NeLM-Area/Evidence/Disease-Focused-Reviews/Acceleration-and-augmentation-of-antidepressants-with-lithium-for-depressive-disorders-two-meta-analyses-of-randomized-placebo-controlled-trials/

· Utility of monitoring mycophenolic acid in solid organ transplant patients http://www.nelm.nhs.uk/en/NeLM-Area/Evidence/Drug-Specific-Reviews/Utility-of-monitoring-mycophenolic-acid-in-solid-organ-transplant-patients/

National Library for Health (NLH): http://www.library.nhs.uk
Behind the Headlines:
· Height and prostate cancer http://www.nhs.uk/news/2008/09September/Pages/Heightandprostatecancer.aspx
· Research shows no MMR–autism link http://www.nhs.uk/news/2008/09September/Pages/ResearchshowsnoMMRautismlink.aspx

NHS Confederation: http://www.nhsconfed.org/
· NHS Confederation comments on patient choice survey findings http://www.nhsconfed.org/issues/mediacentre-listing.cfm/pressrelease/819

NHS Networks: http://www.networks.nhs.uk/
· NHS Next Stage Review, Our vision for primary and community care newsletter http://www.networks.nhs.uk/news.php?nid=2380

PJ Online: http://www.pjonline.com
· Two stroke treatments are equivalent http://www.pjonline.com/news/two_stroke_treatments_are_equivalent
· Reduction in heart rate could reduce coronary artery disease morbidity http://www.pjonline.com/news/reduction_in_heart_rate_could_reduce_coronary_artery_disease_morbidity

Scottish Medicines Consortium (SMC): http://www.scottishmedicines.org/
Accepted for use within NHS Scotland:

· Ropinorole prolonged release (Requip XL) for the treatment of idiopathic Parkinson's Disease. It is accepted for use in patients already taking ropinirole immediate release tablets and in whom adequate symptomatic control has been established.
Accepted for restricted use within NHS Scotland:

· Pemetrexed (Alimta) as monotherapy for second line treatment of patients with locally advanced or metastatic non-small cell lung cancer other than predominantly squamous cell histology. It is restricted to use in patients with good performance status who would otherwise be eligible for treatment with docetaxel.

· Rituximab (MabThera) for the treatment of previously untreated patients with stage III-IV follicular lymphoma in combination with chemotherapy. Rituximab is restricted to use only by haematologists or oncologists who have expertise in treating lymphoma. It should be administered in a healthcare environment where full resuscitation facilities are available.

· Micafungin (Mycamine) for the treatment of invasive candidiasis. It is restricted to use in the treatment of invasive candidiasis in adults, elderly, and children (including neonates).

· Alemtuzumab (MabCampath) for the treatment of patients with B-cell chronic lymphocytic leukaemia (B-CLL) for whom fludarabine combination chemotherapy is not appropriate. It is restricted to use in patients with previously untreated B-CLL, with the cytogenetic abnormality 17p-deletion.
Not recommended for use within NHS Scotland:

· Aripiprazole (Abilify) for the treatment of moderate to severe manic episodes in bipolar I disorder and for the prevention of a new manic episode in patients who experienced predominantly manic episodes and whose manic episodes responded to aripiprazole treatment.
TNSMI Health News (formerly Presswatch Health News) http://www.presswatch.com/health/

Headlines: http://www.presswatch.com/health/?d=2008-09-08#1
· 10 ways to cut the costs of being sick
· 58 in uniforms
· Study links mobile phones to tumours
· Weekly jab offers hope for diabetes sufferers
· Prince's alternative therapist sued by double amputee
· NHS and Health Sector News

The provision of a link to an item on eCAB shall not be taken as an endorsement of any kind. Please read the eCAB Terms and Conditions at http://www.npc.co.uk/pdf/terms_and_conditions/npc_tandcs.pdf.
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Butlletí e-CAB (Novetats 27-08-08)

The National Prescribing Centre's Current Awareness Bulletin (eCAB) contains links to the latest health news, including clinical news, health and social care guidance, publications and policy.

27 August 2008
National Prescribing Centre (NPC): http://www.npc.co.uk
· MeReC Monthly No.5 - August 2008 NICE publishes guidance on CV risk assessment and lipid modification http://www.npc.co.uk/MeReC_Monthly/monthly_august_2008.html
BBC Health News: http://news.bbc.co.uk/1/hi/health/default.stm
· Patients to get sight-saving drug http://news.bbc.co.uk/1/hi/health/7582242.stm
· Drug 'may slow down Parkinson's' http://news.bbc.co.uk/1/hi/health/7583657.stm
Clinical Knowledge Summaries (PRODIGY) / SCHINN: http://www.cks.library.nhs.uk/whats_new
Draft CKS topics available for comments:
· Breast pain – cyclical http://cks.library.nhs.uk/draft_breast_pain_cyclical
· CVD risk assessment and management http://cks.library.nhs.uk/draft_cvd_risk_assessment_and_management
· Diabetes Type 2 http://cks.library.nhs.uk/draft_diabetes_type_2
· Lipid modification - CVD prevention http://cks.library.nhs.uk/draft_lipid_modification_cvd_prevention
· Molluscum contagiosum http://cks.library.nhs.uk/draft_molluscum_contagiosum
· Obsessive compulsive disorder http://cks.library.nhs.uk/draft_obsessive_compulsive_disorder
· Shoulder pain http://cks.library.nhs.uk/draft_shoulder_pain
· Vitiligo http://cks.library.nhs.uk/draft_vitiligo
Department of Health (DH): http://www.dh.gov.uk
· Pharmacy in England: Building on strengths - delivering the future: proposals for legislative change http://www.dh.gov.uk/en/Consultations/Liveconsultations/DH_087324
InfoPOEMs: http://www.essentialevidenceplus.com/
· Pioglitazone does not increase cardiovascular events (PROactive) http://www.essentialevidenceplus.com/infopoems/dailyInfoPOEM.cfm?view=122016
Medicines Management NetWork: http://www.mmnetwork.nhs.uk
· Medicine Digest issues: 576 and 577 http://www.mmnetwork.nhs.uk/med-man-new-details.php?newsid=1671
Midlands Therapeutics Review & Advisory Committee (MTRAC): http://www.keele.ac.uk/schools/pharm/MTRAC/
· UPDATE: Goserelin Verdict/Summary [VS08/12] http://www.keele.ac.uk/schools/pharm/MTRAC/ProductInfo/verdicts/G/Goserelin.pdf
· UPDATE: Leuprorelin Verdict/Summary [VS08/13] http://www.keele.ac.uk/schools/pharm/MTRAC/ProductInfo/verdicts/L/Leuprorelin.pdf
· NEW: Goserelin ESCA http://www.keele.ac.uk/schools/pharm/MTRAC/Latest/documents/GoserelinESCA.doc
National electronic Library for Medicines (NeLM): http://www.nelm.nhs.uk
· Guidance on the diagnosis and management of PVL-associated Staphylococcus aureus infections in England http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Guidance-on-the-diagnosis-and-management-of-PVL-associated-Staphylococcus-aureus-infections-in-England/
· Tight glucose control in critically ill patients doesn't affect mortality and may cause harm http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Tight-glucose-control-in-critically-ill-patients-doesnt-affect-mortality-and-may-cause-harm/
· Heavy-metal contamination common in Ayurvedic medicines http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Heavy-metal-contamination-common-in-Ayurvedic-medicines/
· Abatacept comparable to infliximab for rheumatoid arthritis? http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Abatacept-comparable-to-infliximab-for-rheumatoid-arthritis/
· Review: Patient adherence in COPD http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Review-Patient-adherence-in-COPD/
· Amifostine lowers risk of cisplatin-related hearing loss in children? http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Amifostine-lowers-risk-of-cisplatin-related-hearing-loss-in-children-/
· Studies find mycophenolate mofetil of no short-term benefit in myasthenia gravis http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Studies-find-mycophenolate-mofetil-of-no-short-term-benefit-in-myasthenia-gravis/
· Conference report: Earlier use of rasagiline associated with more improvement in Parkinson’s disease? http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/27/Conference-report-Earlier-use-of-rasagiline-associated-with-more-improvement-in-Parkinsons-disease/
· NICE and NPSA: Technical patient safety solutions for ventilator-associated pneumonia in adults http://www.nelm.nhs.uk/en/NeLM-Area/Evidence/Adverse-Effects-And-Their-Prevention/NICE-and-NPSA-Technical-patient-safety-solutions-for-ventilator-associated-pneumonia-in-adults/
National Institute for Health and Clinical Excellence (NICE): http://www.nice.org.uk/
Clinical guidelines:
· Familial hypercholesterolaemia http://www.nice.org.uk/guidance/index.jsp?action=byID&o=12048
Technology appraisals:
· Entecavir for the treatment of chronic hepatitis B http://www.nice.org.uk/guidance/index.jsp?action=byID&o=12046
· Telbivudine for the treatment of chronic hepatitis B http://www.nice.org.uk/guidance/index.jsp?action=byID&o=12052
· Pegaptanib and ranibizumab for the treatment of age-related macular degeneration http://www.nice.org.uk/guidance/index.jsp?action=byID&o=12057
· Pregnancy - routine anti-D prophylaxis for rhesus negative women (review of TA41) http://www.nice.org.uk/guidance/index.jsp?action=byID&o=12047
National Library for Health (NLH): http://www.library.nhs.uk
Behind the Headlines:
· Screening for premature births http://www.nhs.uk/news/2008/08August/Pages/Screeningforprematurebirths.aspx
· Aspirin for coronary heart disease http://www.nhs.uk/news/2008/08August/Pages/Aspirinforcoronaryheartdisease.aspx
Scottish Intercollegiate Guidelines Network (SIGN): http://www.sign.ac.uk/new.html
· Draft guideline available for consultation: Non-pharmacological management of mild to moderate depression http://www.sign.ac.uk/guidelines/drafts/index.html
TNSMI Health News (formerly Presswatch Health News) http://www.presswatch.com/health/
Headlines: http://www.presswatch.com/health/?d=2008-08-27#1
· Toxic metals in Ayurvedic remedies
· Regulator has Sandoz manufacturing concerns
· Hidden risk of skin cancer
· Children aged 10 to be screened for cholesterol
· NHS and Health Sector News
The provision of a link to an item on eCAB shall not be taken as an endorsement of any kind. Please read the eCAB Terms and Conditions at http://www.npc.co.uk/pdf/terms_and_conditions/npc_tandcs.pdf.
For an explanation of the eCAB selection criteria, please see http://www.npc.co.uk/pdf/eCAB_scope.pdf.
For a copy of the NPC privacy policy please see http://www.npc.co.uk/pdf/terms_and_conditions/npc_privacy_policy.pdf.
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eCAB. Butlletí 26 Agost 2008

The National Prescribing Centre's Current Awareness Bulletin (eCAB) contains links to the latest health news, including clinical news, health and social care guidance, publications and policy.

26 August 2008

National Prescribing Centre (NPC): http://www.npc.co.uk

· MeReC Monthly No.5 - August 2008 NICE publishes guidance on CV risk assessment and lipid modification http://www.npc.co.uk/MeReC_Monthly/monthly_august_2008.html

NPCi Blog http://www.npci.org.uk/blog/

· MeReC Stop Press: FDA safety warning for exenatide (Byetta) http://www.npci.org.uk/blog/?p=187

· On the Horizon Stop Press: Restrictions on the import of unlicensed melatonin products http://www.npci.org.uk/blog/?p=188

· MeReC Rapid Review: As-needed inhaled corticosteroids for children with asthma — more evidence is required to change practice http://www.npci.org.uk/blog/?p=189

BBC Health News: http://news.bbc.co.uk/1/hi/health/default.stm

· Doctors 'keep cancer drugs quiet' http://news.bbc.co.uk/1/hi/health/7581705.stm

· Daily aspirin in middle-age call http://news.bbc.co.uk/1/hi/health/7576723.stm

· Hope over 'early arthritis test' http://news.bbc.co.uk/1/hi/health/7574707.stm

BMJ: http://bmj.com/

· Health related quality of life after combined hormone replacement therapy http://www.bmj.com/cgi/content/full/337/aug21_2/a1190

· Role of blood pressure in development of early retinopathy in adolescents with type 1 diabetes: prospective cohort study http://www.bmj.com/cgi/content/full/337/aug26_1/a918?q=rss_home

· Truly independent research? http://www.bmj.com/cgi/content/short/337/aug21_1/a1332

· End of the free lunch? http://www.bmj.com/cgi/content/full/337/aug26_1/a1399?q=rss_home

British Medical Association (BMA): http://www.bma.org.uk/

· BMA response to new information on polyclinics http://www.bma.org.uk/pressrel.nsf/wlu/GFLR-7HRKCN?OpenDocument&vw=wfmms

Department of Health (DH): http://www.dh.gov.uk

· Guidance on the diagnosis and management of PVL-associated Staphylococcus aureus infections (PVL-SA) in England http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_087173

InfoPOEMs: http://www.essentialevidenceplus.com/

· Gestational diabetes screening: Insufficient evidence of benefit http://www.essentialevidenceplus.com/infopoems/dailyInfoPOEM.cfm?view=122022

· NICE guidelines for lipid lowering http://www.essentialevidenceplus.com/infopoems/dailyInfoPOEM.cfm?view=122019

· NICE guidelines for diabetes mellitus, type 2 http://www.essentialevidenceplus.com/infopoems/dailyInfoPOEM.cfm?view=122017

Medicines and Healthcare products Regulatory Agency (MHRA): http://www.mhra.gov.uk/

· Press release: Devices regulator warns parents of faulty Baby Sleepsafe Monitors http://www.mhra.gov.uk/NewsCentre/Pressreleases/CON023330

National electronic Library for Medicines (NeLM): http://www.nelm.nhs.uk

· EC approves marketing authorisation for duloxetine (Cymbalta) for generalised anxiety disorder http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/EC-approves-marketing-authorisation-for-duloxetine-Cymbalta-for-generalised-anxiety-disorder/

· US FDA issues alert to healthcare professionals regarding natalizumab and progressive multifocal http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/US-FDA-issues-alert-to-healthcare-professionals-regarding-natalizumab-and-progressive-multifocal-leukoencephalopathy/

· Warfarin use may not increase osteoporosis risk in men http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/Warfarin-use-may-not-increase-osteoporosis-risk-in-men/

· NPC iblog discusses study on inhaled corticoteroids for children with asthma http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/NPC-iblog-discusses-study-on-inhaled-corticoteroids-for-children-with-asthma/

· Treatment of extensively drug-resistant TB is feasible http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/Treatment-of-extensively-drug-resistant-TB-is-feasible/

· Meta-analysis: Long-term safety and efficacy of percutaneous coronary intervention with stenting and CABG http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/Meta-analysis-Long-term-safety-and-efficacy-of-percutaneous-coronary-intervention-with-stenting-and-CABG/

· Horizon scanning: US FDA approves romiplostim for chronic immune thrombocytopenic purpura http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/Horizon-scanning-US-FDA-approves-romiplostim-for-chronic-immune-thrombocytopenic-purpura/

· Horizon scanning: US FDA approves palonosetron (Aloxi) capsules for prevention of acute chemotherapy-induced nausea and vomiting http://www.nelm.nhs.uk/en/NeLM-Area/News/2008---August/26/Horizon-scanning-US-FDA-approves-palonosetron-Aloxi-capsules-for-prevention-of-acute-chemotherapy-induced-nausea-and-vomiting/

National Library for Health (NLH): http://www.library.nhs.uk

Behind the Headlines:

· Not just dogs linked to snoring http://www.nhs.uk/news/2008/08August/Pages/Snoringanddogs.aspx

· Effects of HRT on sleep and sex http://www.nhs.uk/news/2008/08August/Pages/EffectsofHRTonsleepandsex.aspx

Prescription Pricing Division, NHSBSA (PPD): http://www.ppa.org.uk/index.htm

· Compensation Arrangements: January - May 2008 http://www.ppa.org.uk/news/compensation_arrangements.htm

TNSMI Health News (formerly Presswatch Health News) http://www.presswatch.com/health/

Headlines: http://www.presswatch.com/health/?d=2008-08-26#1

· Diabetes linked to caesarean babies

· Hopes grow for new diabetes treatment

· Cancer risk in your fry-up

· Poor suffer as the health gap gets wider

· Insects provide final sting to a miserable summer

· Scorpion venom fights tumours

· NHS and Health Sector News

The provision of a link to an item on eCAB shall not be taken as an endorsement of any kind. Please read the eCAB Terms and Conditions at http://www.npc.co.uk/pdf/terms_and_conditions/npc_tandcs.pdf.

For an explanation of the eCAB selection criteria, please see http://www.npc.co.uk/pdf/eCAB_scope.pdf.

For a copy of the NPC privacy policy please see http://www.npc.co.uk/pdf/terms_and_conditions/npc_privacy_policy.pdf.

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